Label-Free Biosensor Based on Coreless-Fiber-Coupled Microcavity for Protein Detection

Citation

Wu, J., Wang, Q., Song, B., Zhang, C., Liu, B., Lin, W., Duan, S., & Bai, H. (2021). Label-Free Biosensor Based on Coreless-Fiber-Coupled Microcavity for Protein Detection. IEEE Photonics Technology Letters. doi: 10.1109/LPT.2021.3071970.

Keywords

• BSA concentration detection
• fiber-optic biosensor
• microfabrication

Brief

The article proposes and experimentally demonstrates a compact, label-free biosensor based on a coreless-fiber-coupled microcavity fabricated by on-line cutting-welding for protein (BSA) detection, showing a sensitivity of 1.602 nm/(mg/ml) by discriminating samples through spectral characteristics.

Summary

The paper demonstrates a compact, label-free fiber biosensor using a coreless-fiber microcavity fabricated by an on-line cutting-welding method. It successfully detects protein (BSA) concentration by analyzing spectral shifts, showing a sensitivity of 1.602 nm/(mg/ml) and offering advantages like miniature size and cost-effectiveness.

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