High-density fiber optic array technology and its applications in functional genomic studies
Citation
FAN, J., CHE, D., ZHAO, C., ZHOU, L., & FENG, W. (2003). High-density fiber optic array technology and its applications in functional genomic studies. Chinese Science Bulletin, 48(18), 1903-1905. DOI: 10.1360/03wc0092
Keywords
- High-density fiber optic array technology
- Functional genomic studies
- DNA microarray technology
- mRNA splicing variants detection
- Single-nucleotide polymorphisms (SNPs)
- Parallel analysis
- Multiplex screening
- Miniaturized array
- Beads
- Oligonucleotide probes
- Hybridization
Brief
The article introduces high-density fiber optic array technology as a novel platform for parallel analysis in functional genomic studies, offering potential improvements over traditional DNA microarrays, particularly in detecting mRNA splicing variants and single-nucleotide polymorphisms (SNPs).
Summary
This article introduces high-density fiber optic array technology as a new tool for functional genomic studies, offering potential improvements over traditional DNA microarrays. This technology, which uses arrays of beads with oligonucleotide probes, allows for parallel analysis and is particularly useful for detecting mRNA splicing variants and single-nucleotide polymorphisms (SNPs), with potential for cost-effective, high-throughput screening in clinical settings.
Origin: https://sci.bban.top/pdf/10.1007/bf03183975.pdf#