Combined optical coherence tomography and hyperspectral imaging using a double-clad fiber coupler

Citation

Guay-Lord, R., Attendu, X., Lurie, K. L., Majeau, L., Godbout, N., Ellerbee Bowden, A. K., Strupler, M., & Boudoux, C. (2016). Combined optical coherence tomography and hyperspectral imaging using a double-clad fiber coupler. Journal of Biomedical Optics, 21(11), 116008. https://doi.org/10.1117/1.JBO.21.11.116008

Keywords

  • Optical coherence tomography (OCT)
  • Hyperspectral imaging (HSI)
  • Double-clad optical fiber coupler (DCFC)
  • Dual-modality imaging
  • Three-dimensional (3-D) acquisition
  • Sample morphology
  • Molecular information
  • Reflectance spectrum
  • Tissue identification
  • Clinical endoscopic applications
  • Tissue characterization
  • Diagnosis
  • Surgical guidance
  • Single-mode core
  • Inner cladding
  • Multimode channel
  • Swept-source OCT
  • White light source
  • Spectrometer
  • Healing epithelial tissue
  • Wavelength-swept laser

Brief

This article demonstrates a novel method for combining Optical Coherence Tomography (OCT) for 3D morphology and Hyperspectral Imaging (HSI) for molecular information by using a double-clad optical fiber coupler in a single imaging probe.

Summary

Researchers successfully combined Optical Coherence Tomography (OCT) for 3D structural imaging and Hyperspectral Imaging (HSI) for molecular information into a single imaging probe by utilizing a double-clad optical fiber coupler (DCFC). The core of the fiber is used for OCT, while the inner cladding collects reflectance spectra for HSI. This dual-modality system allows for simultaneous acquisition of both morphological and molecular data, which could improve tissue identification, diagnosis, and surgical guidance in clinical applications. The system's feasibility was demonstrated by imaging healing epithelial tissue.

Origin: https://doi.org/10.1117/1.JBO.21.11.116008

Back to blog

Leave a comment