Development of Imprinted Polymer Microchannel Capillary Chip for Capillary Electrochromatography

Citation

The article, "Development of Imprinted Polymer Microchannel Capillary Chip for Capillary Electrochromatography" was written by Katsumi Uchiyama, Wei Xu, Makie Yamamoto, Takuya Shimosaka, and Toshiyuki Hoho. It was published in the journal Analytical Sciences, volume 15, in September 1999. The page range of the article is 825-826.

Keywords

  • Capillary electrophoresis
  • Microchannel
  • Convex mold
  • Polymer microchip
  • Electrochromatography
  • Laser-induced fluorescence

Brief

A novel high-pressure gel loading system is developed to automate microfabricated capillary array electrophoresis microchannel plates for enhanced efficiency in DNA analysis. This technology allows for rapid loading of separation media, efficient cleaning, and drying of microchannel plates, making it a crucial step towards an integrated platform for high-throughput genetic analysis.

Summary

The article, "Development of Imprinted Polymer Microchannel Capillary Chip for Capillary Electrochromatography," published in Analytical Sciences in September 1999, describes a new method for creating polymer microchannels for use in capillary electrophoresis. The authors created a convex mold for the microchannel using a mask blanks plate. This mold allowed them to create polymer microchannels with a variety of designs on the inner surface. They successfully created a polyester microchannel and tested it using Sulforhodamine B. The authors found that adding methacrylic acid to the polyester increased the electroosmotic flow due to the increase in carboxyl groups. This new method for creating polymer microchannels could be useful for a variety of applications, including capillary electrophoresis and electrochromatography.

Origin: https://www.jstage.jst.go.jp/article/analsci/15/9/15_9_825/_pdf

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